49832-68-0Relevant academic research and scientific papers
Rh(III)-catalyzed C8 arylation of quinoline N-oxides with arylboronic acids
Huang, Yuanqiong,Lv, Xueli,Song, Hongjian,Liu, Yuxiu,Wang, Qingmin
, p. 1572 - 1575 (2020)
Herein, we report the first RhIII-catalyzed regioselective C8 arylation of quinoline N-oxides with commercially available arylboronic acids as coupling partners. This procedure is simple, and the reaction shows perfect regioselectivity, a broad substrate scope, and isolated yields of up to 92percent. We demonstrate the utility of the reaction by using it for late-stage functionalization of a fungicide.
