49832-69-1Relevant academic research and scientific papers
Rh(III)-catalyzed C8 arylation of quinoline N-oxides with arylboronic acids
Huang, Yuanqiong,Lv, Xueli,Song, Hongjian,Liu, Yuxiu,Wang, Qingmin
, p. 1572 - 1575 (2019/12/24)
Herein, we report the first RhIII-catalyzed regioselective C8 arylation of quinoline N-oxides with commercially available arylboronic acids as coupling partners. This procedure is simple, and the reaction shows perfect regioselectivity, a broad substrate scope, and isolated yields of up to 92percent. We demonstrate the utility of the reaction by using it for late-stage functionalization of a fungicide.
2 - (1 H) - quinoline compound of microwave-assisted synthesis method (by machine translation)
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Paragraph 0069; 0070, (2018/09/28)
The invention belongs to the field of organic intermediate synthesis, in particular discloses a 2 - (1 H) - quinoline compound of microwave-assisted synthetic method: quinoline raw material, and water in a reaction promoter and microwave under the assistance of the addition reaction, to obtain the 2 - (1 H) - quinoline compound; the quinoline raw material is quinoline, or on the quinoline ring in addition to the 2 other than the position of the substituent on the quinoline derivatives containing; the reaction accelerator is 2 - chloroethyl ester and/or 2 - [...] ester. The method raw materials are easy, simple reaction conditions, the reaction time is short, green energy-saving, reaction selectivity and high yield, excellent substrate functional group compatibility, and has high application value. (by machine translation)
