498539-44-9

Upstream product

• 72471-11-5 methyl 6-deoxy-6-amino-2,3,4-tri-O-benzyl-α-D-glucopyranoside 
• 498539-40-5 [3S,4S,5R,6R]-3-O-tert-butyl(dimethyl)silyl-6-tert-butyl(dimethyl)silyloxymethyl-4,5-O-(1-methylethylidene)-3,4,5-trihydroxycyclohexan-1-one 
• 359011-65-7 [3S,4S,5R,6R]-3-O-tert-butyl(dimethyl)silyl-6-tert-butyl(dimethyl)silyloxymethyl-4,5-O-(1-methylethylidene)-3,4,5-trihydroxycyclohexan-1-one 1,3-propanedithioketal 
• 243978-58-7 [3S,4S,5R,6R]-3-O-tert-butyl(dimethyl)silyl-6-hydroxymethyl-4,5-O-(1-methylethylidene)-3,4,5-trihydroxycyclohexan-1-one 1,3-propanedithioketal 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 637330-08-6 methyl 2,3,4-tri-O-benzyl-6-deoxy-6-{[(1R,2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)cyclohexyl]amino}-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis and glycosidase inhibitory activity of aminocyclitols with a C6- or a C7-ring

The synthesis of carbasugars and various aminocyclitols, related to voglibose and acarbose used in the treatment of non-insulino-dependant diabetes, is described from C2-symmetrical bis-epoxides derived from D-mannitol. The methodology involves

New azadisaccharide analogs as potential antidiabetics

The synthesis of various aminocyclitols displaying a N-substituted (or unsubstituted) polyhydroxycyclohexylamine structure is described. The strategy relies on two key steps: a tandem alkylation-cyclization of a C2-symmetrical bis-epoxide deriv