498554-25-9

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 498554-23-7 {(1S,2R,3R,5R,8R,10S,12Z,14R)-2-(tert-butyldimethylsilyloxy)-5-phenyl-4,6,9,15-tetraoxatricyclo[8.5.0.0^3,8]pentadec-12-en-14-yl}methanol 
• 498554-18-0 {(1S,2R,4R,7R,9S,10S)-12,12,14,14-tetraisopropyl-4-phenyl-3,5,8,11,13,15-hexaoxa-12,14-disilatricyclo[8.5.0.0^2,7]pentadec-9-yl}methyl trifluoromethanesulfonate 
• 498554-14-6 {(1S,2R,4R,7R,9S,10S)-12,12,14,14-tetraisopropyl-4-phenyl-3,5,8,11,13,15-hexaoxa-12,14-disilatricyclo[8.5.0.0^2,7]pentadec-9-yl}methanol 
• 784157-61-5 (5aS,5bR,7R,9aR,11aR)-11-(allyloxy)-2,2,4,4-tetraisopropyl-7-phenylhexahydro[1,3]dioxino[4',5':5,6]pyrano[3,4-f] [1,3,5,2,4]trioxadisilepine 
• 498554-19-1 (1S,2R,4R,7R,9S,10S)-9-allyl-12,12,14,14-tetraisopropyl-4-phenyl-3,5,8,11,13,15-hexaoxa-12,14-disilatricyclo[8.5.0.0^2,7]pentadecane 
• 498554-13-5 (1S,2R,4R,7R,10R)-12,12,14,14-tetraisopropyl-9-methylene-4-phenyl-3,5,8,11,13,15-hexaoxa-12,14-disilatricyclo[8.5.0.0^2,7]pentadecane 
• 498554-00-0 (1R,3R,6R,8S,9S,10S)-8-allyl-10-(tert-butyldimethylsilyloxy)-3-phenyl-2,4,7-trioxabicyclo[4.4.0]dec-9-yl acrylate 
• 498554-12-4 4,6-O-benzylidene-2,3-O-(3,5-diisopropyl-2,6-dimethyl-4-oxa-3,5-disilaheptane-3,5-diyl)-D-glucono-1,5-lactone 
• 498553-97-2 (1S,2R,3R,5R,8R,10S,12Z)-2-(tert-butyldimethylsilyloxy)-14-methylene-5-phenyl-4,6,9,15-tetraoxatricyclo[8.5.0.0^3,8]pentadec-12-ene 
• 498553-99-4 (1S,2S,3R,5R,8R,10S,12Z)-2-(tert-butyldimethylsilyloxy)-5-phenyl-4,6,9,15-tetraoxatricyclo[8.5.0.0^3,8]pentadec-12-en-14-one 
• 498554-21-5 (1R,3R,6R,8S,9S,10R)-8-allyl-10-(tert-butyldimethylsilyloxy)-3-phenyl-2,4,7-trioxabicyclo[4.4.0]decan-9-ol 
• 498554-20-4 (1S,3R,6R,8S,9R,10R)-8-allyl-3-phenyl-2,4,7-trioxabicyclo[4.4.0]decane-9,10-diol 

Downstream Products

• 498554-28-2 (1S,3Z,5R,7R,8S,9S,10R)-8-benzyloxy-5-(4-bromobenzyloxymethyl)-10-hydroxymethyl-6,11-dioxabicyclo[5.4.0]undec-3-en-9-ol 
• 498554-27-1 (1R,2R,3S,5R,8R,10S,12Z,14R)-2-benzyloxy-14-(4-bromobenzyloxymethyl)-5-phenyl-4,6,9,15-tetraoxatricyclo[8.5.0.0^3,8]pentadec-12-ene 
• 498554-29-3 (1S,3Z,5R,7R,8S,9S,10R)-8-benzyloxy-5-(4-bromobenzyloxymethyl)-10-(tert-butyldimethylsilyloxymethyl)-6,11-dioxabicyclo[5.4.0]undec-3-en-9-ol 
• 498554-31-7 {(1S,3Z,5R,7R,8S,9S,10R)-8-benzyloxy-9-(4-bromobenzyloxy)-5-(4-bromobenzyloxymethyl)-6,11-dioxabicyclo[5.4.0]undec-3-en-10-yl}methanol 
• 498554-30-6 (1S,3Z,5R,7R,8S,9S,10R)-8-benzyloxy-9-(4-bromobenzyloxy)-5-(4-bromobenzyloxymethyl)-10-(tert-butyldimethylsilyloxymethyl)-6,11-dioxabicyclo[5.4.0]undec-3-ene 
• 498554-32-8 {(1S,3Z,5R,7R,8S,9S,10R)-8-benzyloxy-9-(4-bromobenzyloxy)-5-(4-bromobenzyloxymethyl)-6,11-dioxabicyclo[5.4.0]undec-3-en-10-yl}methyl trifluoromethanesulfonate 
• 498554-26-0 (1R,2R,3S,5R,8R,10S,12Z,14R)-14-(4-bromobenzyloxymethyl)-5-phenyl-4,6,9,15-tetraoxatricyclo[8.5.0.0^3,8]pentadec-12-en-2-ol 

Relevant academic research and scientific papers

Synthesis of the AB-ring segment for the convergent construction of the left half in ciguatoxin

The synthesis of the AB-ring segment aiming at the convergent construction of the left half in ciguatoxin (CTX1B) has been achieved by a strategy based on ring-closing metathesis (RCM) and diastereocontrolled hydroboration to cyclic vinyl ethers.