498573-81-2

Basic information

• Product Name: (S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE
• Synonyms: (S)-TETRAHYDROFURAN-2-CARBOXAMIDE;(S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE
• CAS NO: 498573-81-2
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.13
• Product Categories: Amides;Chiral Compounds;Chiral Building Blocks;Furans;Heterocyclic Building Blocks
• Mol File: 498573-81-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 82-86 °C(lit.)
• Boiling Point: 305.7 °C at 760 mmHg
• Flash Point: 198.8 °C
• Appearance: /
• Density: 1.172 g/cm³
• PKA: 15.50±0.20(Predicted)
• CAS DataBase Reference: (S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE(498573-81-2)
• EPA Substance Registry System: (S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE(498573-81-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 498573-81-2(Hazardous Substances Data)

Usage

Uses

(S)-(?)-Tetrahydrofuran-2-carboxamide can be used as a precursor for the preparation of (S)-tetrahydrofuran-2-carbonitrile (THFCN) via dehydration reaction using thionyl chloride and DMF. THFCN can be further methylated with methylmagnesium chloride (Grignard reagent) to produce (S)-1-(tetrahydrofuran-2-yl)ethenone.

Downstream Products

• 539820-24-1 (S)-tetrahydrofuran-2-carbonitrile