499-23-0Relevant articles and documents
Novel Water-Soluble Bisphosphinite Chiral Ligands Derived from α,α- And β,β-Trehalose. Application to Asymmetric Hydrogenation of Dehydroamino Acids and Their Esters in Water or an Aqueous/ Organic Biphasic Medium
Yonehara, Koji,Hashizume, Tomohiro,Mori, Kenji,Ohe, Kouichi,Uemura, Sakae
, p. 5593 - 5598 (2007/10/03)
Novel 2,3:4,6-di-O-isopropylidene-α-D-glucopyranosyl-(1,1)-4,6-O-isopropylidene- 2,3-di-O-diphenylphosphino-α-D-glucopyranoside (2), 2,3:4,6-di-O-cyclohexylidene-α-D-glucopyranosyl-(1,1)-4,6-O- cyclohexylidene-2,3-di-O-diphenylphosphino-α-D-glucopyranoside (4), and 2,3:4,6-di-O-cyclohexylidene-β-D-glucopyranosyl-(1,1)-4,6-O- cyclohexylidene-2,3-di-O-diphenylphosphino-β-D-glucopyranoside (11) were prepared from the corresponding α,α- or β,β-trehalose. The ligands were transformed into cationic Rh complexes, such as [Rh(α-D-glucopyranosyl-(1,1)-2,3-di-O-diphenylphosphino-α-D- glucopyranoside)(cod)]BF4 (3) and [Rh(β-D-glucopyranosyl-(1,1)-2,3-di-O-diphenylphosphino-β-D- glucopyranoside)(cod)]BF4 (12) bearing free hydroxy groups. These complexes were soluble in water and were efficient catalysts for the asymmetric hydrogenation of dehydroamino acids and their esters in water or an aqueous/organic biphasic medium with high enantioselectivity (up to 99.9% ee). Aqueous biphasic systems offer an easy separation of the aqueous catalyst phase from the product phase and allow recycling of the catalyst phase without the loss of enantioselectivity.
Synthesis and glycosylation shift of 1,1'-disaccharides
Nishizawa,Kodama,Yamane,Kayano,Hatakeyama,Yamada
, p. 982 - 984 (2007/10/02)
Nineteen kinds of nonreducing 1,1'-disaccharides have synthesized by modified Koenigs-Knorr method, and characterized by NMR. The glycosylation shift of each anomeric carbon has been estimated.
A NOVEL OBSERVATION ON KOENIGS-KNORR CONDENSATION OF 2,3,4,6-TETRA-O-ACETYL-α-D-GLUCOPYRANOSYL BROMIDE WITH METHYL 4,6-O-BENZYLIDENE-α-D-GLUCOPYRANOSIDE
Temeriusz, Andrzej,Piekarska, Boguslawa,Radomski, Jan,Stepinski, Janusz
, p. 141 - 147 (2007/10/02)
As a result of condensation between methyl 4,6-O-benzylidene-α-D-glucopyranoside and bromo-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose in 1,2-dichloroethane in presence of silver carbonate, after removal of functional groups, the following substances were ob