499126-36-2Relevant academic research and scientific papers
FeCl3 mediated arylidenation of carbohydrates
Basu, Nabamita,Maity, Sajal K.,Roy, Soumik,Singha, Shuvendu,Ghosh, Rina
experimental part, p. 534 - 539 (2011/04/27)
Glycosides and thioglycosides based on monosaccharides in reaction with benzaldehyde dimethylacetal or p-methoxybenzaldehyde dimethyl acetal undergo FeCl3-catalyzed (20 mol %) regioselective 4,6-O-arylidenation producing the corresponding acetals in high yields. FeCl3 also mediates acetalation of glycosides and thioglycosides of cellobiose, maltose, and lactose affording the corresponding 4′,6′-O-benzylidene acetals, which were isolated after their acetylation in situ with acetic anhydride and pyridine. The combined yields (two steps) of these final products are also high (61-84%). The procedure is applicable to a wide variety of functional groups including -OBn.
Synthesis of oligosaccharides corresponding to Streptococcus pneumoniae type 9 capsular polysaccharide structures
Alpe, Mia,Oscarson, Stefan
, p. 1715 - 1722 (2007/10/03)
Two trisaccharides, α-D-Galp-(1→3)-β-D-ManpNAc-(1→4)-β-D-Glcp and α-D-Glcp-(1→3)-β-D-ManpNAc-(1→4)-β-D-Glcp, corresponding to structures from Streptococcus pneumoniae capsular polysaccharides type 9A, L, V and type 9N, respectively, have been synthesised
