499137-81-4

Basic information

• Product Name: Benzonitrile, 4-methoxy-2-[[(4-phenylcyclohexylidene)amino]oxy]-
• CAS NO: 499137-81-4
• Molecular Formula: C20H20N2O2
• Molecular Weight: 320.391
• Mol File: 499137-81-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-methoxy-2-[[(4-phenylcyclohexylidene)amino]oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-methoxy-2-[[(4-phenylcyclohexylidene)amino]oxy]-(499137-81-4)
• EPA Substance Registry System: Benzonitrile, 4-methoxy-2-[[(4-phenylcyclohexylidene)amino]oxy]-(499137-81-4)

Safety Data

• Hazardous Substances Data: 499137-81-4(Hazardous Substances Data)

Upstream product

• 4500-20-3 4-phenylcyclohexanone oxime 
• 94610-82-9 2-fluoro-4-methoxyphenyl nitrile 
• 4894-75-1 1-phenyl-4-cyclohexanone 

Downstream Products

• 4894-75-1 1-phenyl-4-cyclohexanone 
• 157368-82-6 6-methoxy-3-amino-1,2-benzisoxazole 

Relevant articles and documents

Application of aryloximes as solid-phase ketone linkers.

In both solution and the solid phase, a variety of ketone oxime anions have been treated with 4-substituted-2-fluorobenzonitriles to give the corresponding nucleophilic aromatic substitution aryloxime adducts. Under aqueous acidic conditions, these adducts underwent cyclization to give the corresponding ketones. Suzuki and amide coupling reactions were also successfully performed on two resin-bound oximes followed by subsequent cyclorelease to give ketone product in good yields and purities. [reaction--see text]