499149-88-1Relevant academic research and scientific papers
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs
Asada, Masaki,Obitsu, Tetsuo,Kinoshita, Atsushi,Nagase, Toshihiko,Yoshida, Tadahiro,Yamaura, Yoshiyuki,Takizawa, Hiroya,Yoshikawa, Ken,Sato, Kazutoyo,Narita, Masami,Nakai, Hisao,Toda, Masaaki,Tobe, Yoshito
, p. 3212 - 3223 (2010)
A series of 3-(2-aminocarbonylphenyl)propanoic acid analogs possessing the (1R)-1-(3,5-dimethylphenyl)-3-methylbutylamine moiety on the carboxyamide side chain were synthesized and evaluated for their binding affinity for the EP1-4 receptors and their ant
