499157-67-4Relevant academic research and scientific papers
3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs
Asada, Masaki,Obitsu, Tetsuo,Kinoshita, Atsushi,Nagase, Toshihiko,Yoshida, Tadahiro,Yamaura, Yoshiyuki,Takizawa, Hiroya,Yoshikawa, Ken,Sato, Kazutoyo,Narita, Masami,Nakai, Hisao,Toda, Masaaki,Tobe, Yoshito
experimental part, p. 3212 - 3223 (2010/07/08)
A series of 3-(2-aminocarbonylphenyl)propanoic acid analogs possessing the (1R)-1-(3,5-dimethylphenyl)-3-methylbutylamine moiety on the carboxyamide side chain were synthesized and evaluated for their binding affinity for the EP1-4 receptors and their ant
CARBOXYLIC ACID DERIVATIVE COMPOUNDS AND DRUGS COMPRISING THESE COMPOUNDS AS THE ACTIVE INGREDIENT
-
Page 550, (2010/02/07)
A carboxylic acid derivative of formula (I): wherein R1 is-COOH,-COOR6, etc.; A is a single bond, alkylene, etc.; R2 is alkyl, alkoxy, etc.; B is a carbocyclic ring or a heterocyclic ring; Q is alkylnene-Cyc2, etc.; D is a linking chain; and R3 is alkyl,
