499159-79-4

Usage

General Description

1H-Cyclobut[e]indene-1,2,4-triol, 2,5,6,7-tetrahydro-3-methoxy-, (1R,2S)-rel- (9CI) is a chemical compound with the molecular formula C12H14O4. It is a tetrahydroindazole derivative and a synthetic analogue of natural cannabinoids, with potential use in the treatment of pain, anxiety, and inflammation. 1H-Cyclobut[e]indene-1,2,4-triol, 2,5,6,7-tetrahydro-3-methoxy-, (1R,2S)-rel- (9CI) has been researched for its potential therapeutic effects on the endocannabinoid system, which plays a vital role in various physiological processes in the body. However, further studies are needed to fully understand its pharmacological properties and potential medical applications.

Relevant academic research and scientific papers

Regioselective synthesis of substituted o-alkoxyphenol derivatives through thermal benzannulation of Fischer (alkenylcyclobutenyl)carbene complexes

A convenient, regioselective, and general synthetic method for producing highly substituted o-phenol-containing polycycles from Fischer (alkenylcyclobutenyl)carbene complexes has been described. The starting complexes have been synthesized by means of the [2 + 2] cycloaddition reaction of (alkenylethynyl)carbene complexes and a range of enol ethers, and in most cases, they have proven to be stable at room temperature and therefore isolable. The key step of the synthesis consists of the thermal benzannulation reaction of these novel pentacarbonyl dienyl Fischer complexes, which is an unprecedented transformation for these kinds of complexes. The unexpected behavior of (alkenylcyclobutenyl)carbene complexes has been rationalized in terms of their geometries.