499188-13-5Relevant academic research and scientific papers
Transition metal-free N-arylation of secondary amides through iodonium salts as aryne precursors
Wang, Ming,Huang, Zhijian
supporting information, p. 10185 - 10188 (2016/11/11)
By using a diaryliodonium salt as a benzyne precursor, a transition metal-free approach for N-arylation of secondary amides is developed. This novel benzyne precursor, which can be prepared easily by a one step process from an aryl iodide, shows different reactivities with previous benzyne precursors in the N-arylation reaction. Mechanistic studies confirm the involvement of benzyne species (generated in situ from the diaryliodonium salts) as key intermediates.
Conformational studies of tertiary oligo-m-benzanilides and oligo-p-benzanilides in solution
Chabaud, Laurent,Clayden, Jonathan,Helliwell, Madeleine,Page, Abigail,Raftery, James,Vallverdú, Lluís
experimental part, p. 6936 - 6957 (2010/10/02)
A series of oligo-m- and p-benzanilides were made and their conformations in solution were studied by NMR. In most cases, conformational mixtures were observed as soon as three or more monomers were incorporated into the oligomer. Some crystal structures were obtained, which indicated that helical conformations were adopted in the solid state.
