499202-20-9 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
1,2-Benzenediol, also known as catechol, is the parent compound from which the derivative is formed.
Explanation
The addition of a trifluoro-1-hydroxyethyl group to the catechol structure creates a derivative with unique properties.
Explanation
The presence of a chiral center in the molecule results in two possible enantiomers (mirror-image isomers). The (1R) configuration indicates the specific arrangement of atoms around the chiral center.
Explanation
The presence of three fluorine atoms in the 2,2,2-trifluoro-1-hydroxyethyl group can influence the compound's reactivity, stability, and lipophilicity.
Explanation
The hydroxyl groups in the catechol structure and the 1-hydroxyethyl group contribute to the compound's polarity and hydrogen bonding capabilities.
Explanation
The unique properties of the compound, such as its reactivity and biological activity, may make it useful in various fields, pending further research and development.
Explanation
The introduction of the trifluoro-1-hydroxyethyl group can change the reactivity of the compound compared to its parent compound, catechol.
Explanation
The presence of the trifluoro-1-hydroxyethyl group may affect the compound's interaction with biological systems, which could be explored for potential applications in medicine or other fields.
Explanation
Additional research and analysis are needed to fully understand the compound's properties, reactivity, and potential applications in various industries.
Parent Compound
1,2-Benzenediol (Catechol)
Derivative
3-[(1R)-2,2,2-trifluoro-1-hydroxyethyl] group
Chirality
(1R) configuration
Fluorination
Trifluoro substitution
Hydroxylation
Presence of hydroxyl groups
Potential Applications
Pharmaceuticals, agrochemicals, or other industrial applications
Reactivity
Altered due to trifluoro-1-hydroxyethyl group
Biological Activity
Potentially influenced by the trifluoro-1-hydroxyethyl group
Further Studies
Required to determine specific properties and uses
Check Digit Verification of cas no
The CAS Registry Mumber 499202-20-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,9,2,0 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 499202-20:
(8*4)+(7*9)+(6*9)+(5*2)+(4*0)+(3*2)+(2*2)+(1*0)=169
169 % 10 = 9
So 499202-20-9 is a valid CAS Registry Number.
499202-20-9Relevant academic research and scientific papers
A comparative study of the synthesis of 3-substituted catechols using an enzymatic and a chemoenzymatic method
Berberian,Allen,Sharma,Boyd,Hardacre
, p. 727 - 739 (2008/02/09)
A series of cis-dihydrodiol metabolites, available from the bacterial dioxygenase-catalysed oxidation of monosubstituted benzene substrates using Pseudomonas putida UV4 , have been converted to the corresponding catechols using both a heterogeneous catalyst (Pd/c) and a naphthalene cis-diol dehydrogenase enzyme present in whole cells of the recombinant strain Escherichia coli DH5α(pUC129: nar B). A comparative study of the merits of both routes to 3-substituted catechols has been carried out and the two methods have been found to be complementary. A similarity in mechanism for catechol formation under both enzymatic and chemoenzymatic conditions, involving regioselective oxidation of the hydroxyl group at C-1, has been found using deuterium labelled toluene cis-dihydrodiols. The potential, of combining a biocatalytic step (dioxygenase-catalysed cis-dihydroxylation) with a chemocatalytic step (Pd/C-catalysed dehydrogenation), into a one-pot route to catechols, from the parent substituted benzene substrates, has been realised.
Tandem enzyme-catalysed oxidations of alkyl phenyl sulfides and alkyl benzenes: enantiocomplementary routes to chiral phenols.
Boyd, Derek R,Sharma, Narain D,Ljubez, Vera,Byrne, Breige E,Shepherd, Steven D,Allen, Christopher C R,Kulakov, Leonid A,Larkin, Michael J,Dalton, Howard
, p. 1914 - 1915 (2007/10/03)
Dioxygenase-catalysed trioxygenation of alkyl phenyl sulfides and alkyl benzenes yields enantiopure cis-dihydrodiol sulfoxides and triols respectively; naphthalene cis-dihydrodiol dehydrogenase-catalysed aromatisation of these diastereoisomers gives enant
