499217-06-0Relevant articles and documents
Using smell to triage samples in point-of-care assays
Mohapatra, Hemakesh,Phillips, Scott T.
supporting information, p. 11145 - 11148 (2013/01/15)
Smell of success: Reagent 1 provides the dual readouts of odor (ethanethiol) and fluorescence (derivative of 7-hydroxycoumarin) and can be used in down-selection assays based on smell and quantitative fluorescence assays of the samples that give a positive result. An important feature of 1 is the matched sensitivity of the two outputs. This reagent is designed for use in resource-limited settings and is demonstrated in assays that detect enzymes. Copyright
Tetrahydroquinoline derivatives as antithrombotic agents
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Page 60, (2010/02/05)
This invention relates generally to tetracyclic tetrahydroquinoline compounds, and analogues thereof, and pharmaceutically acceptable salt forms thereof, which are selective inhibitors of serine protease enzymes, especially factor VIIa; pharmaceutical compositions containing the same; and methods of using the same as anticoagulant agents for modulation of the coagulation cascade.