4994-89-2 Usage
Description
5,6-DIMETHYL-THIENO[2,3-D]PYRIMIDIN-4-YLAMINE is a thieno pyrimidine derivative with a molecular formula C8H9N3S. It features a thienopyrimidine skeleton substituted with a dimethylamino group at position 4. This chemical compound is recognized for its biological activity and is primarily utilized as a pharmaceutical intermediate in the synthesis of various drugs and pharmaceutical compounds. Its potential applications in the development of new medications for different therapeutic indications make it a valuable component in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
5,6-DIMETHYL-THIENO[2,3-D]PYRIMIDIN-4-YLAMINE is used as a pharmaceutical intermediate for the synthesis of various drugs and pharmaceutical compounds. Its role in this industry is crucial as it aids in the development of new medications for a range of therapeutic indications. 5,6-DIMETHYL-THIENO[2,3-D]PYRIMIDIN-4-YLAMINE's specific properties and uses are tailored to the particular applications and formulations in which it is incorporated, highlighting its versatility and importance in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 4994-89-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,9 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4994-89:
(6*4)+(5*9)+(4*9)+(3*4)+(2*8)+(1*9)=142
142 % 10 = 2
So 4994-89-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H9N3S/c1-4-5(2)12-8-6(4)7(9)10-3-11-8/h3H,1-2H3,(H2,9,10,11)
4994-89-2Relevant articles and documents
Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors
Sleebs, Brad E.,Nikolakopoulos, George,Street, Ian P.,Falk, Hendrik,Baell, Jonathan B.
, p. 5992 - 5994 (2011/10/18)
4-Aminobenzothieno[3,2-d]pyrimidines were previously identified in a high throughput screening campaign as LIMK1 inhibitors. Scaffold reversal led to the identification of a series of simple 5,6-substituted 4-aminothieno[2,3-d] pyrimidines with low micromolar inhibition of LIMK1.
Synthesis and anti-microbial activity of some heterocycles: Part-II
Rahman, Khandker M. M.,Shaifullah Chowdhury,Bhuiyan,Hossain,Uddin
, p. 95 - 98 (2007/10/03)
Thieno[2,3-d]pyrimidines (2), (3) and (4) have been obtained via the reaction of 2-amino-4, 5-dimethylthiophen-3-carbonitrile (1) with formamide, acetonitrile and benzonitrile respectively. Treatment of (2), (3) and (4) with chloroacetaldehyde respectivel