499775-94-9

Upstream product

• 499775-91-6 ethyl (E)-3-[4-hydroxy-2,6-bis(methoxymethyl)-5-pyrimidinyl]-2-propenoate 
• 499775-92-7 ethyl (E)-3-[4-chloro-2,6-bis(methoxymethyl)-5-pyrimidinyl]-2-propenoate 
• 499775-90-5 5-iodo-2,6-bis(methoxymethyl)-4-pyrimidinol 
• 3122-77-8 2,6-bis(methoxymethyl)-4-pyrimidinol 
• 41051-15-4 4-methoxyacetoacetic acid methylester 
• 499775-93-8 ethyl (E)-3-[4-(4-bromo-benzylamino)-2,6-bis(methoxymethyl)-5-pyrimidinyl]-2-propenoate 

Relevant academic research and scientific papers

Novel human metabolites of the angiotensin-II antagonist tasosartan and their pharmacological effects.

Three novel metabolites of the angiotensin-II (A-II) receptor antagonist tasosartan have been identified in humans, and the syntheses and pharmacologic profiling of these metabolites are reported. Each metabolite bound the human A-II receptor with IC(50)s