Xn:Harmful;499785-45-4Relevant academic research and scientific papers
Another application of (NH4)42[MoVI 72MoV 60O372(CH3COO)30(H2O)72] as a highly efficient recyclable catalyst for the synthesis of dihy
Rohaniyan, Marziyeh,Davoodnia, Abolghasem,Nakhaei, Ahmad
, p. 626 - 629 (2016/07/19)
In continuation of our previous works on the application of (NH4)42[MoVI 72MoV 60O372(CH3COO)30(H2O)72], a Keplerate-type giant-ball n
Design, synthesis, docking study and biological evaluation of some novel tetrahydrochromeno [3′,4′:5,6]pyrano[2,3-b]quinolin-6(7H)-one derivatives against acetyl- and butyrylcholinesterase
Khoobi, Mehdi,Alipour, Masoumeh,Moradi, Alireza,Sakhteman, Amirhossein,Nadri, Hamid,Razavi, Seyyede Faeze,Ghandi, Mehdi,Foroumadi, Alireza,Shafiee, Abbas
, p. 291 - 300 (2013/10/01)
Novel hybrid derivatives of two known scaffolds; tetrahydroaminoquinoline and coumarin were synthesized and evaluated for both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities. By means of an efficient nanocatalyst, the reaction time for the syntheses of the target compounds was reduced. Subsequently, Ellman's modified method was used to evaluate the enzyme inhibitory activity of the synthesized structures. It was observed that most hybrid structures were moderate to potent inhibitors of AChE compared to Tacrine as the reference drug among which 7f with 4-fluorophenyl substituent was the most active compound (IC50 = 5 nM).
Mono- and bis-2-amino-4h-pyrans: Alum catalyzed three - or pseudo five-component reaction of 4-hydroxycoumarin, malononitrile and aldehydes
Karimi, Ali Reza,Eslami, Cyrus
, p. 150 - 154 (2013/01/10)
An efficient method for the three- Or pseudo five-component synthesis of mono- and bis-2-amino-4H-pyrans in excellent yields using Alum (KAl(SO 4)2.12H2O) as recyclable catalyst is described. The present methodology offers
