499795-63-0

Upstream product

• 1004-40-6 6-Amino-2-thiouracil 
• 18440-58-9 1-(N-phenylhydrazono)-1-chloropropanone 

Downstream Products

• 1621260-32-9 12-acetyl-7-methyl-10-phenyl-6H-chromeno[4′,3′:4,5] pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-6,14-(10H)-dione 
• 1309462-28-9 3-acetyl-6-[(1,7-diphenyl-1,5-dihydro-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)]-1-phenyl-1,5-dihydropyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-one 

Relevant academic research and scientific papers

A convenient synthesis of novel derivatives of pyrido[2,3-d][1,2,4] triazolo[4,3-a]pyrimidine-5,6-dione

Reaction of 6-Amino-2-thiouracil with hydrazonoyl halides yielded regioselectively 7-amino-1,3-disubstituted-1,2,4-triazolo[4,3-a]pyrimidine derivatives. Upon treatment with methyl (Z)2-benzoylamino-3-dimethylaminopropenoate, the corresponding methyl (Z)-2-benzoylamino-3-([1,2,4]triazolo[4,3-a]pyrimidin-7-yl)-amino propenoates were obtained which cyclized in the presence of sodium ethoxide to afford novel derivatives of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-5,6-(1H, 8H)-diones.