499797-06-7Relevant academic research and scientific papers
Synthesis of highly functionalized phenylalanine derivatives via cross-enyne metathesis reactions
Kotha, Sambasivarao,Halder, Somnath,Brahmachary, Enugurthi
, p. 9203 - 9208 (2007/10/03)
A new method for the synthesis of constrained phenylalanine derivatives is described. In this regard, the simple synthesis of acyclic diene building blocks embodying an α-amino acid moiety has been achieved. The diene building blocks have been prepared by cross enyne-metathesis reaction as a key step. The Diels-Alder reaction of the dienes with a dienophile such as dimethyl acetylenedicarboxilate (DMAD) followed by oxidation of the resulting cycloadduct gave highly substituted phenylalanine derivatives.
Synthesis of unusual α-amino acid derivatives via cross-enyne metathesis reaction
Kotha, Sambasivarao,Halder, Somnath,Brahmachary, Enugurthi,Ganesh, Thota
, p. 853 - 855 (2007/10/03)
Various highly functionalized phenylalanine derivatives are prepared via cross-enyne metathesis and Diels-Alder reaction as key steps.
