4998-15-6Relevant articles and documents
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Karrer,Musante
, p. 1140,1142 (1935)
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An efficient synthesis of polyfunctionalized pyrroles by three-component reaction of arylglyoxals, Meldrum’s acid and ethyl 2-chloro-3-(arylamino)but-2-enoates
Anary-Abbasinejad, Mohammad,Nezhad-shahrokhabadi, Fereshteh
, (2022/01/19)
A fast and convenient method for synthesis of some new functionalized pyrrole derivatives have been described via a three-component reaction between arylglyoxals, Meldrum’s acid and ethyl 2-chloro-3-(arylamino)but-2-enoate derivatives in excellent yields.
One-pot synthesis of stable phosphorus ylides by three-component reaction between arylglyoxals, phosphines and barbituric or Meldrum’s acid
Latifi, Mahsa,Anary-Abbasinejad, Mohammad
, p. 133 - 139 (2022/01/28)
An efficient one-pot method for the synthesis of new substituted phosphorus ylides is described via three-component reaction between arylglyoxals, C–H acids such as barbituric acid and Meldrum’s acid and triphenylphosphine or tri-n-octylphosphine. This re
A novel class for carbonic anhydrases inhibitors and evaluation of their non-zinc binding
Kuzu, Burak,Tan, Meltem,Gül?in, ?lhami,Menges, Nurettin
, (2021/06/09)
In this study, 23 different imidazole derivatives were synthesized, and the inhibitory properties of these derivatives against carbonic anhydrase I and II isoenzymes were investigated for the first time. The inhibition concentrations of the imidazole derivatives were found to be in the range of 2.89–115.5 nM. Docking studies examined the binding properties of the imidazole derivatives, and the structure–activity relationship is discussed. Theoretical calculations showed that the binding mode of the imidazole ring was non-zinc binding.