50-34-0 Usage
Chemical Properties
white crystalline powder
Uses
Different sources of media describe the Uses of 50-34-0 differently. You can refer to the following data:
1. Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.
2. anticholinergic
3. A muscarinic acetylcholine receptor antagonist
General Description
Different sources of media describe the General Description of 50-34-0 differently. You can refer to the following data:
1. Propantheline bromide,2-hydroxy-ethyl)diisopropylmethylammonium bromidexanthene-9-carboxylate (Pro-Banthine), is prepared in amanner exactly analogous to that used for methanthelinebromide. It is a white, water-soluble, crystalline substance,with properties quite similar to those of methantheline bromide.Its chief difference from methantheline bromide is inits potency, which has been estimated variously to be 2 to5 times as great.
2. White crystals or white powder. Melting point 159-161°C .Used therapeutically as an anticholinergic.
Air & Water Reactions
Water soluble.
Health Hazard
SYMPTOMS: Symptoms of exposure to Propantheline bromide include dilated pupils and blurred vision; increased intraocular tension and heart rate; hot, dry, red skin; dry mouth; disorientation; hallucinations; aggressive behavior; rapid pulse and respiration; convulsions; and coma.
Fire Hazard
Flash point data are not available for Propantheline bromide , but Propantheline bromide is probably combustible.
Biochem/physiol Actions
Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.
Veterinary Drugs and Treatments
In small animal medicine propantheline bromide has been used for
its antispasmodic/antisecretory effects in the treatment of diarrhea.
It is also employed in the treatment of hyperreflexic detrusor or
urge incontinence and as oral treatment in anticholinergic responsive
bradycardias. In horses, propantheline has been used intravenously
to reduce colonic peristalsis and for relaxing the rectum to
allow easier rectal examination and surgery.
Check Digit Verification of cas no
The CAS Registry Mumber 50-34-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 50-34:
(4*5)+(3*0)+(2*3)+(1*4)=30
30 % 10 = 0
So 50-34-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H
