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5-amino-2-(2-deoxypentofuranosyl)-1,2,4-triazin-3(2H)-one, also known as 5-amino-2-deoxycytidine, is a nucleoside analog with a unique chemical structure. It consists of a 1,2,4-triazin-3(2H)-one core, which is a six-membered heterocyclic ring containing three nitrogen atoms, and a 2-deoxypentofuranosyl group attached to the 2-position of the triazine ring. This sugar moiety is a modified version of the pentofuranosyl group found in natural nucleosides, lacking an oxygen atom at the 2' position. The 5-amino group on the triazine ring is responsible for the compound's basic properties. This chemical is of interest in medicinal chemistry due to its potential as an antiviral agent, particularly against herpes simplex virus. It functions by inhibiting viral DNA synthesis, making it a valuable compound in the development of antiviral therapies.

50-92-0

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50-92-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 50-92-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50-92:
(4*5)+(3*0)+(2*9)+(1*2)=40
40 % 10 = 0
So 50-92-0 is a valid CAS Registry Number.

50-92-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-amino-2-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazin-3-one

1.2 Other means of identification

Product number -
Other names 2'-deoxy-6-azacytidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50-92-0 SDS

50-92-0Downstream Products

50-92-0Relevant academic research and scientific papers

Analysis of an Active Deformylation Mechanism of 5-Formyl-deoxycytidine (fdC) in Stem Cells

Sch?n, Alexander,Kaminska, Ewelina,Schelter, Florian,Ponkkonen, Eveliina,Korytiaková, Eva,Schiffers, Sarah,Carell, Thomas

supporting information, p. 5591 - 5594 (2020/03/04)

The removal of 5-methyl-deoxycytidine (mdC) from promoter elements is associated with reactivation of the silenced corresponding genes. It takes place through an active demethylation process involving the oxidation of mdC to 5-hydroxymethyl-deoxycytidine

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