500015-33-8

Upstream product

• 500014-74-4 (1-methyl-5-nitro-1H-indol-2-yl)methanol 
• 71056-58-1 5-amino-1-methyl-1H-indole-2-carboxylic acid ethyl ester 

Downstream Products

• 500015-32-7 1-(2-hydroxymethyl-1-methyl-1H-indol-5-yl)-3-(4-phenoxyphenyl)urea 
• 1314127-08-6 4-[(1-hydroxycyclopropyl)ethynyl]-N-(1-methyl-2-{[(2-methylpropyl)amino]methyl}-1H-indol-5-yl)benzamide 
• 1314127-07-5 N-(2-{[(2,2-dimethylpropyl) amino]methyl}-1-methyl-1H-indol-5-yl)-4-[(1-hydroxycyclopropyl)ethynyl]benzamide 
• 1314127-06-4 N-(2-{[(2,2-dimethylpropyl)amino]methyl}-1-methyl-1H-indol-5-yl)-4-[(1-hydroxycyclobutyl)ethynyl]benzamide 
• 1314127-05-3 4-[(1-hydroxycyclobutyl)ethynyl]-N-(2-{[(2-methylpropyl)amino]methyl}-1-methyl-1H-indol-5-yl)benzamide 
• 1314128-08-9 4-bromo-N-(2-{[(2,2-dimethylpropyl)amino]methyl}-1-methyl-1H-indol-5-yl)benzamide 
• 1314128-07-8 4-bromo-N-(1-methyl-2-{[(2-methylpropyl)amino]methyl}-1H-indol-5-yl)benzamide 
• 1314128-06-7 4-bromo-N-(2-formyl-1-methyl-1H-indol-5-yl)benzamide 

Relevant academic research and scientific papers

INDOLE DERIVATIVE

The present invention provides an indole derivative having a melanin-concentrating hormone receptor antagonistic action, which is useful as an agent for the prophylaxis or treatment of obesity and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals

The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, which are valuable pharmaceutically active compounds that are suitable, for example, for the treatment of obesity, type II diabetes, arteriosclerosis, high blood pressure, paresthesia, depression, anxiety, anxiety neuroses, schizophrenia, disorders associated with the circadian rhythm, and drug abuse, as well as normalizing lipid metabolism.