500131-50-0 Usage
General Description
N,N-Diethyl-alpha,alpha-difluoro-3-methylbenzylamine is a chemical compound with the molecular formula C12H16F2N. It is a fluoroalkylamine that is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. N,N-Diethyl-alpha,alpha-difluoro-3-methylbenzylamine is primarily utilized in the production of antihistamine medications, particularly those that work as H1 receptor antagonists. It is also used as a building block in the development of other pharmaceuticals and agrochemicals, as well as in the synthesis of specialty chemicals. Additionally, it can be employed as a reagent in organic chemistry reactions to introduce the difluoromethyl group into organic molecules. N,N-Diethyl-alpha,alpha-difluoro-3-methylbenzylamine should be handled and stored with care, as it is flammable and may cause irritation if it comes into contact with the skin or eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 500131-50-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,1,3 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 500131-50:
(8*5)+(7*0)+(6*0)+(5*1)+(4*3)+(3*1)+(2*5)+(1*0)=70
70 % 10 = 0
So 500131-50-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H17F2N/c1-4-15(5-2)12(13,14)11-8-6-7-10(3)9-11/h6-9H,4-5H2,1-3H3
500131-50-0Relevant articles and documents
METHOD FOR PRODUCING FLUOROAMINE
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Page/Page column 6-7, (2009/04/23)
Provided is a one-step efficient production method for an α,α-difluoroamine of a general formula (1) from an amide compound. The method is an economical method capable of producing the intended α,α-difluoroamine at high yield by reacting a starting amide
A facile synthesis of oxazolines, thiazolines, and imidazolines using α,α-difluoroalkylamines
Fukuhara, Tsuyoshi,Hasegawa, Chihiro,Hara, Shoji
, p. 1528 - 1534 (2008/02/05)
β-Amino alcohols, β-amino thiols, and β-diamines can be converted to the corresponding oxazoline, thiazoline, and imidazoline derivatives, respectively, by reaction with α,α-difluoroalkylamines under mild conditions. The reaction is applicable for the synthesis of optically active heterocyclic compounds. Georg Thieme Verlag Stuttgart.
PROCESS FOR PRODUCING OPTICALLY ACTIVE FLUOROCHEMICAL
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Page/Page column 6, (2008/06/13)
The present invention provides a process for producing an optically active fluoro compound represented by formula (3) through reaction between a specific fluoroamine and an optically active diol; and a process for producing an optically active fluoroalcoh
