500229-80-1 Usage
General Description
(R)-tert-Butyl 4-hydroxy-2-oxopiperidine-1-carboxylate, also known as (R)-tert-Butyl 4-hydroxy-2-oxopiperidine-1-carboxylate, is a chemical compound used in the synthesis of pharmaceuticals and other biologically active molecules. It is a chiral compound with a tert-butyl ester group, a hydroxyl group, and a piperidine ring with a ketone group. (R)-tert-Butyl 4-hydroxy-2-oxopiperidine-1-carboxylate is used as a building block in the production of various drugs and organic molecules due to its unique chiral structure and reactivity. It is important in the field of organic chemistry and pharmaceutical research, as it plays a crucial role in the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 500229-80-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,2,2 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 500229-80:
(8*5)+(7*0)+(6*0)+(5*2)+(4*2)+(3*9)+(2*8)+(1*0)=101
101 % 10 = 1
So 500229-80-1 is a valid CAS Registry Number.
500229-80-1Relevant articles and documents
CCR2 MODULATORS
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Paragraph 0269, (2016/12/07)
Compounds are provided that are modulators of the CCR2 receptor. The compounds have the general formula (I) and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activtation of CCR2 receptors.
Regio- and stereoselective hydroxylation of N-substituted piperidin-2-ones with Sphingomonas sp. HXN-200
Chang, Dongliang,Feiten, Hans-Juergen,Witholt, Bernard,Li, Zhi
, p. 2141 - 2147 (2007/10/03)
High activity, excellent regioselectivity, and opposite enantioselectivity were achieved in the hydroxylation of N-benzyl- and N-tert-butoxycarbonylpiperidin-2-one with Sphingomonas sp. HXN-200. High yield preparations of 4-hydroxypiperidin-2-ones were demonstrated in a bioreactor and in a shaking flask by use of the frozen/thawed cells as biocatalyst. The absolute configuration for the bioproducts was established.
