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1,8-Naphthyridine-3-carboxamide, N-cyclopropyl-1,4-dihydro-1-[3-[(1-oxido-3-pyridinyl)ethynyl]phenyl]-4-ox o- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

500355-52-2

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500355-52-2 Usage

Chemical class

Naphthyridine

Structural components

Cyclopropyl group, pyridinyl group, amide group, and ethynyl group

Presence of an oxo group

Indicates potential reactivity and ability to participate in various chemical reactions

Biological and pharmacological properties

Likely diverse due to the structurally diverse components

Potential applications

Wide range of potential applications due to its complex nature

Research interest

Of interest in various fields of research due to its complex structure and potential properties

Check Digit Verification of cas no

The CAS Registry Mumber 500355-52-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,3,5 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 500355-52:
(8*5)+(7*0)+(6*0)+(5*3)+(4*5)+(3*5)+(2*5)+(1*2)=102
102 % 10 = 2
So 500355-52-2 is a valid CAS Registry Number.

500355-52-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide

1.2 Other means of identification

Product number -
Other names MK-0873

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:500355-52-2 SDS

500355-52-2Downstream Products

500355-52-2Relevant academic research and scientific papers

Alternative Forms of the Phosphodiesterase-4 Inhibitor N-Cyclopropyl-1--4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxyamide

-

, (2011/10/13)

The present invention is directed to alternative forms of the title phosphodiesterase 4 inhibitor which has the structural formula shown immediately below:

Optimization and structure-activity relationship of a series of 1-phenyl-1,8-naphthyridin-4-one-3-carboxamides: Identification of MK-0873, a potent and effective PDE4 inhibitor

Guay, Daniel,Boulet, Louise,Friesen, Richard W.,Girard, Mario,Hamel, Pierre,Huang, Zheng,Laliberte, France,Laliberte, Sebastien,Mancini, Joseph A.,Muise, Eric,Pon, Doug,Styhler, Angela

scheme or table, p. 5554 - 5558 (2009/06/18)

A SAR study of a series of 1-phenyl-1,8-naphthyridin-4-one-3-carboxamides is described. Optimization of the series was based on in vitro potency against PDE4, inhibition of the LPS-induced production of TNF-α in human whole blood and minimizing affinity f

ALTERNATIVE FORMS OF THE PHOSPHODIESTERASE-4 INHIBITOR N-CYCLOPROPYL-1-{3-[(1-OXIDOPRYIDIN-3-YL)ETHYNYL]PHENYL}-4-OXO-1,4-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXYAMIDE

-

Page/Page column 15; 16, (2010/02/14)

The present invention is directed to alternative forms of the title phosphodiesterase 4 inhibitor which has the structural formula shown immediately below: Compound IX

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