500540-48-7

Upstream product

• 5779-95-3 3,5-dimethylbenzaldehyde 
• 108-67-8 1,3,5-trimethyl-benzene 
• 27129-86-8 1-bromomethyl-3,5-dimethylbenzene 

Downstream Products

• 101789-41-7 1,2-bis(3,5-dimethylphenyl)ethane-1,2-dione 
• 1062158-03-5 1,2-bis-(3,5-dimethyl-phenyl)-2-hydroxy-pent-4-en-1-one 
• 356074-72-1 2,3,4,5-tetrakis-(3,5-dimethyl-phenyl)-1-(2,4,6-trimethyl-phenyl)-cyclopenta-2,4-dienol 
• 356074-74-3 1-(3,5-difluoro-phenyl)-2,3,4,5-tetrakis-(3,5-dimethyl-phenyl)-cyclopenta-2,4-dienol 
• 356074-75-4 1-(2,6-difluoro-phenyl)-2,3,4,5-tetrakis-(3,5-dimethyl-phenyl)-cyclopenta-2,4-dienol 
• 356074-92-5 C₅(3,5-C₆H₃Me₂)4(3,5-C₆H₃F₂)Br 
• 356074-71-0 2,3,4,5-tetrakis-(3,5-dimethyl-phenyl)-1-(2,5-dimethyl-phenyl)-cyclopenta-2,4-dienol 
• 356074-70-9 1,2,3,4,5-pentakis-(3,5-dimethyl-phenyl)-cyclopenta-2,4-dienol 
• 481726-49-2 C₅(3,5-C₆H₃Me₂)5Br 
• 356074-90-3 C₅(3,5-C₆H₃Me₂)4(3,6-C₆H₃Me₂)Br 
• 356074-89-0 C₅(3,5-C₆H₃Me₂)4(3-C₆H₄Me)Br 
• 356074-91-4 C₅(3,5-C₆H₃Me₂)4(3-C₆H₄F) 
• 356074-69-6 2,3,4,5-tetrakis-(3,5-dimethyl-phenyl)-1-m-tolyl-cyclopenta-2,4-dienol 
• 356074-73-2 2,3,4,5-tetrakis-(3,5-dimethyl-phenyl)-1-(3-fluoro-phenyl)-cyclopenta-2,4-dienol 

Relevant academic research and scientific papers

Structure effect of TsDPEN derivatives on enantioselectivity of asymmetric transfer hydrogenation

TsDPEN derivative (3,3′,5,5′-TMTsDPEN) was synthesized and applied in asymmetric transfer hydrogenation of ketones. The influence of chiral ligands' NCCN dihedral angles to the enantioselectivities of the reaction was discussed.

Palladium-catalyzed C-allylation of benzoins and an NHC-catalyzed three component coupling derived thereof: Compatibility of NHC- and Pd-catalysts

(Chemical Equation Presented) A large range of benzoins was successfully applied as C-nucleophiles in the palladium-catalyzed allylic alkylation with several allyl acetates, resulting in functionalized tertiary homoallylic alcohols. A number of unsymmetrical benzoins can be coupled with high levels of regio- and chemoselectivity. Finally, the challenging compatibility of free N-heterocyclic carbenes with a palladium catalyst has been utilized in a number of metal- and organocatalyzed three-component coupling reactions.

A convenient synthesis of bromopentaarylcyclopentadienes containing methyl or fluorine substituents

The ketones C5(3,5-C6H3Me2)4(O) (5b) and C5-2,5(3,5-C6H3Me2) 2(C6H5)2(O) (5c) were prepared and characterized. The pentaarylcyclopentadienols C5(C6H5)4(Ar′)(OH) (Ar′=3,5-C6H3Me2, 6a3; Ar′=2,4,6-C6H2Me3, 6a5; Ar′=3-C6H4F, 6a6; Ar′=3,5-C6H3F2, 6a7), C5(3,5-C6H3Me2) 4(Ar′)(OH) (Ar′=3-C5H4Me, 6b2; 3,5-C5H3Me2, 6b3; 3,6-C5H3Me2, 6b4; 2,4,6-C5H2Me3, 6b5; Ar′=3-C6H4F, 6a6; Ar′=3,5-C6H3F2, 6a7; Ar′=2,6-C6H3F2, 6a8) were obtained by reaction of the corresponding Ar′Li with the ketones C5(C6H5)4(O) (5a), or C5(3,5-C6H3Me2)4(O) (5b). The synthesis and characterization of the bromopentaarylcyclopentadienes C5(C6H5)4(Ar′)(Br) (Ar′=3,5-C6H3Me2, 7a3; Ar′=2,4,6-C6H2Me3, 7a5) and C5(3,5-C6H3Me2) 4(Ar′)(Br) (Ar′=3-C5H4Me, 7b2; 3,5-C5H3Me2, 7b3; 3,6-C5H3Me2, 7b4; 2,4,6-C5H2Me3, 7b5; Ar′=3-C6H4F, 7a6; Ar′=3,5-C6H3F2, 7a7; Ar′=2,6-C6H3F2, 7a8) containing methyl groups or fluorine atoms on the Ar′ rings are reported. The bromopentaarylcyclopentadienes are isolated as a 1:2:2 mixture of three isomers when Ar and Ar′ are different, except when the latter substituent bears two fluorine or two methyl groups in the ortho positions. In these cases the reaction is regiospecific and provides a unique isomer with the di-ortho-substituted arene located in the β-position with respect to the carbon bearing the bromine atom.