500548-63-0Relevant academic research and scientific papers
Total synthesis of (+)-benzastatin E via diastereoselective Grignard addition to 2-acylindoline.
Toda, Narihiro,Ori, Mayuko,Takami, Kazuko,Tago, Keiko,Kogen, Hiroshi
, p. 269 - 271 (2003)
[reaction: see text] A stereoselective total synthesis of (+)-benzastatin E (1) is described. The synthesis involves a diastereoselective Grignard addition to 2-acylindoline 2, which is derived from commercially available (S)-2-indolinecarboxylic acid (3). The unknown absolute configuration of (+)-1 is determined as (9S,10R).
