500554-53-0

Upstream product

• 90137-01-2 1-o-chlorobenzyl-naphthalene 
• 89-98-5 2-chloro-benzaldehyde 
• 703-55-9 1-naphthylmagnesiumbromide 
• 13922-41-3 1-Naphthylboronic acid 
• 22115-41-9 2-(bromomethyl)benzonitrile 

Downstream Products

• 102543-33-9 4'-chloro-2-[1]naphthylmethyl-benzophenone 
• 115293-29-3 2-methoxy-2'-[1]naphthylmethyl-benzophenone 
• 5705-75-9 <2-(1-Naphthyl-methyl)-phenyl>-phenaethyl-keton 
• 36278-07-6 2-(1-Naphthyl-methyl)-phenyl-cyclohexylketon 
• 102319-27-7 2-(1-Naphthylmethyl)-phenyl-propyl-keton 
• 102319-36-8 2-(1-Naphthylmethyl)-phenyl-isopropyl-keton 
• 102751-66-6 2-(1-Naphthylmethyl)-phenyl-tert.butyl-keton 

Relevant academic research and scientific papers

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere via N-H imines as an intramolecular directing group

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere was developed starting from carbonitriles and Grignard reagents via N-H imine intermediates. The present process is characterized by the following two-step sequence in a one-pot manner: (1) addition of Grignard reagents to carbonitriles to form N-H imines and (2) benzylic C-H oxygenation (C=O bond formation) triggered by 1,5-hydrogen atom transfer with transient iminyl copper species.