500709-78-4 Usage
Uses
Used in Pharmaceutical Industry:
2,4-Thiazolidinedione, 5-[5-(4-chlorophenyl)-4-pentynyl]-5-[(4-methoxyphenyl)thio]is used as a potential insulin-sensitizing and anti-diabetic agent for the treatment of type 2 diabetes. Its thiazolidinedione core and additional substituents may enhance its pharmacological activity and therapeutic efficacy in managing insulin resistance and improving glucose metabolism.
Used in Drug Discovery and Development:
2,4-Thiazolidinedione, 5-[5-(4-chlorophenyl)-4-pentynyl]-5-[(4-methoxyphenyl)thio]can be used as a starting point for drug discovery and development. Its unique structure and potential pharmacological properties make it a promising candidate for further research and optimization to develop new drugs with improved efficacy and safety profiles for various medical conditions, including diabetes and other related metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 500709-78-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,7,0 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 500709-78:
(8*5)+(7*0)+(6*0)+(5*7)+(4*0)+(3*9)+(2*7)+(1*8)=124
124 % 10 = 4
So 500709-78-4 is a valid CAS Registry Number.
500709-78-4Relevant academic research and scientific papers
Method of using 5-(arysulfonyl)-, 5-(arylsulfanyl)-and 5-(arylsulfanyl)thiazolidine-2,4-diones for inhibition of farnesyl-protein transferase
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, (2008/06/13)
This invention relates to a method of using novel 5-(arylsulfonyl)-, 5-(arylsulfinyl)- and 5-(arylsulfanyl)thiazolidine-2,4-diones of Formula (1), wherein Ar, Ar′, R6, m and n are as defined in the specification as inhibitors of Ras FPTase, and may be used as an alternative to, or in conjunction with, traditional cancer therapy for treating ras- oncogene-dependent tumors, such as cancers of the pancreas, colon, bladder, and thyroid.
