500757-06-2Relevant academic research and scientific papers
Practical stereoselective synthesis of α-D-C-mannosyl-(R)-alanine
Colombo, Lino,Di Giacomo, Marcello,Ciceri, Paola
, p. 9381 - 9386 (2007/10/03)
α-D-C-Mannosyl-(R)-alanine 2 was synthesized in only four steps starting from the known acetonide protected D-ribo-hex-1-enitol 4 and N-benzoylalanine. The key C-C bond formation between the sugar and the amino acid moieties was effected through a Claisen rearrangement of the intermediate oxazole 7, derived from the ester 6.
