500767-13-5

Basic information

• Product Name: Carbamic acid, [(1S,2S)-3-[[(1S)-1-(aminocarbonyl)-3-methylbutyl]amino]-2-hydroxy-1-( phenylmethyl)propyl]-, 1,1-dimethylethyl ester
• CAS NO: 500767-13-5
• Molecular Formula: C21H35N3O4
• Molecular Weight: 393.527
• Mol File: 500767-13-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S,2S)-3-[[(1S)-1-(aminocarbonyl)-3-methylbutyl]amino]-2-hydroxy-1-( phenylmethyl)propyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S,2S)-3-[[(1S)-1-(aminocarbonyl)-3-methylbutyl]amino]-2-hydroxy-1-( phenylmethyl)propyl]-, 1,1-dimethylethyl ester(500767-13-5)
• EPA Substance Registry System: Carbamic acid, [(1S,2S)-3-[[(1S)-1-(aminocarbonyl)-3-methylbutyl]amino]-2-hydroxy-1-( phenylmethyl)propyl]-, 1,1-dimethylethyl ester(500767-13-5)

Safety Data

• Hazardous Substances Data: 500767-13-5(Hazardous Substances Data)

Upstream product

• 687-51-4 H-L-Leu-NH₂ 
• 98760-08-8 (2R,3S)-3-[N-(tert-butyloxycarbonyl)amino]-1,2-epoxy-4-phenylbutane 

Downstream Products

• 500767-27-1 (2S,5S,6S)-3-aza-3-(benzyloxycarbonyl)-6-[[(tert-butyloxycarbonyl)-L-valinyl]amino]-2-isobutyl-5-hydroxy-7-phenylheptanoyl amide 
• 500767-20-4 (2S,5S,6S)-3-aza-3-(benzyloxycarbonyl)-6-[(tert-butyloxycarbonyl)amino]-2-isobutyl-5-hydroxy-7-phenylheptanoyl amide 

Relevant articles and documents

Design and synthesis of plasmepsin I and plasmepsin II inhibitors with activity in Plasmodium falciparum-infected cultured human erythrocytes

A series of protease inhibitors targeted at the malarial enzymes plasmepsin I and II, and encompassing a basic hydroxyethylamine transition state isostere scaffold, was prepared. The substituents in the P1′ position were varied and the biological activiti