500770-75-2 Usage
General Description
Boc-(S)-3-amino-3-(2-bromo-phenyl)-propionic acid is a chemical compound that contains an amino acid functional group, a bromophenyl group, and a propionic acid group. The Boc in its name refers to the tert-butyloxycarbonyl protective group, which increases the chemical's stability and resistance to unwanted side reactions during a chemical synthesis. It's typically used in peptide synthesis. Due to its bromophenyl group, this compound may exhibit unique electronic or steric interactions, which can be used to alter the properties of a larger chemical structure. Overall, this compound is a valuable chemical building block used in a variety of synthetic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 500770-75-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,7,7 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 500770-75:
(8*5)+(7*0)+(6*0)+(5*7)+(4*7)+(3*0)+(2*7)+(1*5)=122
122 % 10 = 2
So 500770-75-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H18BrNO4/c1-14(2,3)20-13(19)16-11(8-12(17)18)9-6-4-5-7-10(9)15/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)
500770-75-2Relevant articles and documents
2-METHYL-QUINAZOLINES
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Page/Page column 400, (2018/10/19)
The present invention describes 2-methyl-quinazoline compounds of general formula (I), methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions. The 2-methyl substituted quinazoline compounds of general formula(I) effectively and selectively inhibit the Ras-Sos interaction without significantly targeting the EGFR receptor. They are therefore useful for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, such as cancer as a sole agent or in combination with other active ingredients.
