500879-57-2Relevant academic research and scientific papers
Pd-catalyzed one-pot coupling of allylamines, activated alkenes, and unsaturated halides (or triflate): An atom efficient synthesis of highly functionalized pyrrolidines
Martinon, Luc,Azoulay, Stéphane,Monteiro, Nuno,Kündig, E. Peter,Balme, Geneviève
, p. 3831 - 3836 (2004)
A Pd-catalyzed three-component assembling of highly functionalized 4-benzyl-(and allyl-)pyrrolidines was achieved based on a combination of allyl amines, gem-diactivated alkenes, and unsaturated halides (or triflate).
Three-component one-pot synthesis of functionalised (Z)-4-benzylidene (and alkenylidene) pyrrolidines
Azoulay, Stéphane,Monteiro, Nuno,Balme, Geneviève
, p. 9311 - 9314 (2002)
A three-component synthesis of stereodefined 4-benzylidene-(or alkenylidene)-pyrrolidines from simple, readily available starting materials is described. This one-pot process is initiated by a conjugate addition of a propargylamine to a gem-diactivated olefin subsequently followed by a carbopalladation involving an aryl halide (or vinyl triflate).
