501031-12-5Relevant academic research and scientific papers
Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARα/γ dual agonists, and X-ray crystallographic studies
Casimiro-Garcia, Agustin,Bigge, Christopher F.,Davis, Jo Ann,Padalino, Teresa,Pulaski, James,Ohren, Jeffrey F.,McConnell, Patrick,Kane, Christopher D.,Royer, Lori J.,Stevens, Kimberly A.,Auerbach, Bruce J.,Collard, Wendy T.,McGregor, Christine,Fakhoury, Stephen A.,Schaum, Robert P.,Zhou, Hairong
, p. 4883 - 4907 (2008/12/21)
A new series of α-aryl or α-heteroarylphenyl propanoic acid derivatives was synthesized that incorporate acetylene-, ethylene-, propyl-, or nitrogen-derived linkers as a replacement of the commonly used ether moiety that joins the central phenyl ring with
A novel approach to 3-acylated indolizine structures via iodine-mediated hydrative cyclization
Kim, Ikyon,Kim, Sun Gi,Kim, Ji Young,Lee, Ge Hyeong
, p. 8976 - 8981 (2008/03/18)
We have discovered a new route to 3-acylated indolizine structures via iodine-mediated hydrative cyclization. Reaction mechanism is proposed for this novel transformation, which involves a 5-exo-dig iodocyclization, deprotonation, incorporation of another
