501037-44-1Relevant articles and documents
E-Z-izomerization of 2-methylenethiazolidin-4-ones
Morzherin,Kosterina,Berseneva,Dehaen,Bakulev
, p. 1292 - 1297 (2007/10/03)
The equilibrium concentrations of E- and Z-isomers of thiazolidin-4-ones containing exocyclic double bonds in positions 2 and 5 of the cycle were determined in DMSO-d6. The influence of the nature of the substituents on the equilibrium position was found. Electron-releasing substituents stabilize the E,Z-configuration and electron-withdrawing substituents stabilize the Z,Z-configuration. The association constants of E- and Z-2-ethoxycarbonylmethylenethiazolidin-4-ones with the sodium cation were determined by 1H NMR spectroscopy.