501076-48-8

Usage

Uses

Used in Pharmaceutical Industry:
N-(2-AMINO-4 5-DICHLOROPHENYL)ACETAMIDE& is used as an intermediate in the synthesis of pharmaceuticals for its potential medicinal properties. Its structural features and functional groups allow for the development of new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, N-(2-AMINO-4 5-DICHLOROPHENYL)ACETAMIDE& serves as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its chemical structure contributes to the effectiveness of these products in controlling pests and weeds in agricultural settings.
Used in Organic Synthesis:
N-(2-AMINO-4 5-DICHLOROPHENYL)ACETAMIDE& is utilized in organic synthesis processes due to its reactive functional groups, which can be further modified or combined with other molecules to create a variety of organic compounds for different applications.
Used in Chemical Manufacturing Processes:
N-(2-AMINO-4 5-DICHLOROPHENYL)ACETAMIDE& is also employed in various chemical manufacturing processes, where its unique structure and properties can be leveraged to produce a range of chemical products, enhancing the efficiency and effectiveness of these processes.
Overall, N-(2-AMINO-4 5-DICHLOROPHENYL)ACETAMIDE& is a valuable chemical intermediate with diverse applications across different industries, making it an important compound for ongoing research and development.

InChI:InChI=1/C8H8Cl2N2O/c1-4(13)12-8-3-6(10)5(9)2-7(8)11/h2-3H,11H2,1H3,(H,12,13)

Upstream product

• 5462-30-6 N-(4,5-dichloro-2-nitrophenyl)acetamide 

Relevant academic research and scientific papers

Highly selective transfer hydrogenation of functionalised nitroarenes using cobalt-based nanocatalysts

Anilines are important feedstock for the synthesis of a variety of chemicals such as dyes, pigments, pharmaceuticals and agrochemicals. The chemoselective catalytic reduction of nitro compounds represents the most important and prevalent process for the manufacture of functionalized anilines. Consequently, the development of selective catalysts for the reduction of nitro compounds in the presence of other reducible groups is a major challenge and is crucial. In this regard, herein we show that the cobalt oxide (Co3O4-NGr@C) based nano-materials, prepared by the pyrolysis of cobalt-phenanthroline complexes on carbon constitute highly selective catalysts for the transfer hydrogenation of nitroarenes to anilines using formic acid as a hydrogen source. Applying these catalysts, a series of structurally diverse and functionalized nitroarenes have been reduced to anilines with unprecedented chemo-selectivity tolerating halides, olefins, aldehyde, ketone, ester, amide and nitrile functionalities.

Nanoscale Fe2O3-based catalysts for selective hydrogenation of nitroarenes to anilines

Production of anilines - key intermediates for the fine chemical, agrochemical, and pharmaceutical industries - relies on precious metal catalysts that selectively hydrogenate aryl nitro groups in the presence of other easily reducible functionalities. Herein, we report convenient and stable iron oxide (Fe2O3) - based catalysts as a more earth-abundant alternative for this transformation. Pyrolysis of iron-phenanthroline complexes on carbon furnishes a unique structure in which the active Fe2O 3 particles are surrounded by a nitrogen-doped carbon layer. Highly selective hydrogenation of numerous structurally diverse nitroarenes (more than 80 examples) proceeded in good to excellent yield under industrially viable conditions.