501097-15-0

Basic information

• Product Name: N-(4-monomethoxytrityl)-3-bromopropylamine
• Synonyms: N-(4-monomethoxytrityl)-3-bromopropylamine
• CAS NO: 501097-15-0
• Molecular Weight: 410.354
• Mol File: 501097-15-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-monomethoxytrityl)-3-bromopropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-monomethoxytrityl)-3-bromopropylamine(501097-15-0)
• EPA Substance Registry System: N-(4-monomethoxytrityl)-3-bromopropylamine(501097-15-0)

Safety Data

• Hazardous Substances Data: 501097-15-0(Hazardous Substances Data)

Upstream product

• 5003-71-4 3-bromopropylamine hydrochloride 
• 14470-28-1 mono-4-methoxytrityl chloride 

Downstream Products

• 501097-31-0 (tert-butoxycarbonyl-{3-[tert-butoxycarbonyl-(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-amino]-propyl}-amino)-acetic acid tert-butyl ester 
• 501097-26-3 [tert-butoxycarbonyl-(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-amino]-acetic acid tert-butyl ester 
• 501097-20-7 [{3-[(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-(2-nitro-benzenesulfonyl)-amino]-propyl}-(2-nitro-benzenesulfonyl)-amino]-acetic acid tert-butyl ester 
• 501097-30-9 (tert-butoxycarbonyl-{3-[(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-(2-nitro-benzenesulfonyl)-amino]-propyl}-amino)-acetic acid tert-butyl ester 
• 501097-16-1 [(3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-propyl)-(2-nitro-benzenesulfonyl)-amino]-acetic acid tert-butyl ester 

Relevant articles and documents

ANTIBODY DRUG CONJUGATES

Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R1, R2 and R3 is H, ORa, OCORa, OCOORa, alkyl, alkenyl, alkynyl, etc; R3' is, CORa, COORa, CONRaRb, etc; each of R4 to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa,alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.; each dotted line represents an optional additional bond; X is an extending group; AA is an amino acid unit; L is a linker group; w is 0to 12; b is 0 or 1; A bis a moiety comprising at least one antigen binding site, and n is the ratio of the group [D-(X) b -(AA)w-(L)-] to the moiety comprising at least one antigen binding site and is in the range from 1 to 20, are useful in the treatment of cancer.