501098-89-1Relevant academic research and scientific papers
Catalytic asymmetric synthesis of 1,3-enyne scaffolds: Design and synthesis of conjugated nitro dienynes as novel Michael acceptors and development of a new synthetic methodology
Li, Xiang,Peng, Fangzhi,Zhou, Mingtao,Mo, Mingjie,Zhao, Ruirui,Shao, Zhihui
, p. 1745 - 1747 (2014/02/14)
A novel catalytic enantioselective synthesis of functionalized 1,3-enynes has been developed featuring the design and synthesis of conjugated nitro dienynes as a useful new class of Michael acceptors. Moreover, a simple, yet flexible catalytic cascade approach to functionalized enantioenriched acyclic α,β-enones and cyclic dienones has also been developed.
Benzannulation of substituted 3-alkoxycarbonylhex-3-en-5-ynoic acids: A new route to 4-substituted 3,5-dihydroxybenzoic acids derivatives
Serra, Stefano,Fuganti, Claudio
, p. 1661 - 1664 (2007/10/03)
A new regioselective pathway to 4-substituted 3,5-dihydroxybenzoic acids derivatives is described here. According to this procedure substituted propargylic aldehydes are converted into substituted 3-alkoxycarbonylhex-3-en-5-ynoic acids, which are in turn, treated with acetic anhydride in the presence of sodium acetate to give the substituted benzoic acids derivatives. The aromatic moiety constructed using the latter benzannulation reaction is formed in regioselective fashion and a range of substituents are tolerated.
Synthesis of alkylidenecyclopentenones and dialkylidenecyclopentenones via the coupling of propargylic alcohol and 2-alkyne-1,4-diol derivatives with cyclopropylcarbene-chromium complexes
Herndon, James W.,Zhu, Jin,Sampedro, Diego
, p. 4985 - 4993 (2007/10/03)
The coupling of propargylic alcohols and their derivatives with cyclopropylcarbene-chromium complexes has been investigated. The coupling reaction leads to alkylidenecyclopentenones or alkoxyalkyl-cyclopentenones, depending on the leaving group ability of
