5012-76-0Relevant academic research and scientific papers
Synthesis of 3-substituted-4(3H)-quinazolinones via HATU-mediated coupling of 4-hydroxyquinazolines with amines
Xiao, Zili,Yang, Michael G.,Li, Peng,Carter, Percy H.
supporting information; experimental part, p. 1421 - 1424 (2009/09/05)
A novel synthesis of 3-substituted 4(3H)-quinazolinones via HATU-mediated coupling of 4-hydroxyquinazolines with primary amines has been developed. Under mild reaction conditions, the products were achieved in good yield from commercially available starti
Convenient synthesis of oxazolidinones and oxazinones from allyl and homoallyl amines under mild conditions
Garcia-Egido, Eduardo,Fernandez, Isabelle,Munoz, Luis
, p. 3029 - 3042 (2007/10/03)
An efficient one-pot general method for the high-yield synthesis in solution of oxazolidinones and oxazinones from allyl- and homoallylamines, respectively, has been developed. The reaction is carried out at an atmospheric pressure between 0°C and room te
Superbase catalysis of oxazolidin-2-one ring formation from carbon dioxide and prop-2-yn-1-amines under homogeneous or heterogenous conditions
Costa, Mirco,Chiusoli, Gian Paolo,Taffurelli, Davide,Dalmonego, Giulio
, p. 1541 - 1546 (2007/10/03)
N-alkyl-substituted prop-2-yn-1-amines and N-tri-, tetra- and penta-alkyl-substituted guanidines or other strong organic bases assemble under the action of carbon dioxide to afford carbamates, from which methyleneoxazolidinones 2 are formed by ring closure. If alkyl or cycloalkyl chains of appropriate length are present in the guanidines the reaction readily occurs under heterogenous conditions without solvent.
