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5012-80-6

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5012-80-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5012-80-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,1 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5012-80:
(6*5)+(5*0)+(4*1)+(3*2)+(2*8)+(1*0)=56
56 % 10 = 6
So 5012-80-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N4OS/c1-3(4(2)9-10)7-8-5(6)11/h7H,1-2H3,(H3,6,8,11)/b4-3+

5012-80-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Diacetyl monoxime thiosemicarbazone

1.2 Other means of identification

Product number -
Other names 3-hydroxyiminobutanone thiosemicarbazone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5012-80-6 SDS

5012-80-6Downstream Products

5012-80-6Relevant articles and documents

Spectral, thermal, electrochemical and analytical studies on Cd(II) and Hg(II) thiosemicarbazone complexes

El-Asmy,El-Gammal,Saleh

, p. 39 - 44 (2008)

The coordination characteristic of the investigated thiosemicarbazones towards hazard pollutants, Cd(II) and Hg(II), becomes the first goal. Their complexes have been studied by microanalysis, thermal, electrochemical and spectral (electronic, IR and MS) studies. The substitutent (salicylaldehyde, acetophenone, benzophenone, o-hydroxy-p-methoxybenzophenone or diacetylmonoxime) plays an important role in the complex formation. The coordination sites were the S for thiosemicarbazide (HTS); NN for benzophenone thiosemicarbazone (HBTS); NS for acetophenone thiosemicarbazone (HATS) and salicylaldehyde thiosemicarbazone (H2STS); NNS or NSO for diacetylmonoxime thiosemicarbazone (H2DMTS). The stability constants of Hg(II) complexes were higher than Cd(II). The kinetic and thermodynamic parameters for the different thermal decomposition steps in the complexes have been evaluated. The activation energy values of the first step ordered the complexes as: [Cd(H2STS)Cl2]H2O > [Cd(H2DAMTS)Cl2] > [Cd(HBTS)2Cl2]2H2O > [Cd(HATS)2Cl2]. The CV of [Cd(H2STS)Cl2]H2O and [Hg(HBTS)Cl2] were recorded. The use of H2DMTS as a new reagent for the separation and determination of Cd(II) ions from water and some synthetic samples using flotation technique is aimed to be discussed.

A pharmaceutical cocrystal with potential anticancer activity

Saha, Rajat,Sengupta, Suman,Dey, Sanjoy Kumar,Steele, Ian M.,Bhattacharyya, Arindam,Biswas, Susobhan,Kumar, Sanjay

, p. 49070 - 49078 (2014/12/11)

The design of pharmaceutical cocrystals has become a prime thrust of crystal engineering and the pharmaceutical industry in recent times-but the use of pharmaceutical cocrystals as regular drugs is yet to be explored. Quinoxaline acts as a basic skeleton of several potential anticancer drugs. We have successfully cocrystallized quinoxaline with another organic molecule 3-thiosemicarbano-butan-2-one-oxime (TSBO, a virus replication inhibitor) and examined the anticancer activity of the cocrystal. The crystal structure of the cocrystal was determined by single crystal X-diffraction study. According to thermogravimetric study the cocrystal exhibits better thermal stability than quinoxaline. UV-Vis spectroscopic study has shown that in solution state the behavior of the cocrystal and the physical mixture of its components (mixture of quinoxaline and TSBO) are significantly different. The solubility of the cocrystal in distilled water has been found to be 31.9 mg mL-1. The cocrystal exhibits a specific cytotoxic effect on lung cancer cells (A549) at 10-7 M concentration while it shows growth inhibitory effect on normal cells. The detailed mechanistic study of the cytotoxicity of the cocrystal suggests that it follows the mitochondrial mediated cell death pathway through activation of Caspase 9 and Bax. It also shows anticancer activity on breast cancer cells (MCF-7). This journal is

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