501328-35-4

Upstream product

• 197369-14-5 2-(4-nitrobenzoyl)-4,5-methylenedioxyphenylacetic acid methyl ester 
• 6974-61-4 β-oxy-α-(3',4'-methylenedioxyphenyl)propane 
• 379733-75-2 trans-7,8-dihydro-7-methyl-5-(4-nitrophenyl)-5H-[1,3]dioxolo[4,5-g][2]benzopyrane 

Relevant academic research and scientific papers

Synthesis and antitumor activity of 1,3-benzodioxole derivatives.

A series of 1,3-benzodioxoles (5-19) was synthesized and evaluated for their in vitro antitumor activity against human tumor cell lines. Some derivatives exhibited tumor growth inhibition activity. In particular, 6-(4-aminobenzoyl)-1,3-benzodioxole-5-acetic acid methyl ester 8, the most active compound of the series, possesses a significant growth inhibitory activity on 52 cell lines at concentrations ranging from 10(-7) to 10(-5) M.