501328-41-2

Upstream product

• 433716-67-7 2-(4-nitrobenzoyl)-4,5-methylenedioxyphenylacetone 
• 501328-38-7 [6-(2-methyl-[1,3]dioxolan-2-ylmethyl)-benzo[1,3]dioxol-5-yl]-(4-nitro-phenyl)-methanone 

Downstream Products

• 501328-42-3 7-methyl-5-(4-nitrophenyl)-5H-1,3-dioxolo[4,5-g][2]benzopyran 
• 433716-68-8 3-methyl-6,7-methylenedioxy-1-(4-nitrophenyl)isoquinoline 

Relevant academic research and scientific papers

Synthesis and antitumor activity of 1,3-benzodioxole derivatives.

A series of 1,3-benzodioxoles (5-19) was synthesized and evaluated for their in vitro antitumor activity against human tumor cell lines. Some derivatives exhibited tumor growth inhibition activity. In particular, 6-(4-aminobenzoyl)-1,3-benzodioxole-5-acetic acid methyl ester 8, the most active compound of the series, possesses a significant growth inhibitory activity on 52 cell lines at concentrations ranging from 10(-7) to 10(-5) M.