501359-37-1 Usage
General Description
1,2,4-Triazolo[4,3-a]pyridine,5-methoxy-(9CI) is a chemical compound with the molecular formula C7H7N3O. It is classified as a pyridine derivative and contains a triazolo ring system. The compound features a methoxy group, which consists of a molecule of methanol where the hydrogen has been replaced by a methyl group. This chemical is useful in pharmaceutical research and drug development due to its potential pharmacological properties. It is commonly used as a building block in the synthesis of various biologically active molecules and has been studied for its potential applications in the treatment of neurological and psychiatric disorders. Additionally, 1,2,4-Triazolo[4,3-a]pyridine,5-methoxy-(9CI) may have other industrial and research uses, but its full range of applications and properties are not yet fully understood.
Check Digit Verification of cas no
The CAS Registry Mumber 501359-37-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,1,3,5 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 501359-37:
(8*5)+(7*0)+(6*1)+(5*3)+(4*5)+(3*9)+(2*3)+(1*7)=121
121 % 10 = 1
So 501359-37-1 is a valid CAS Registry Number.
501359-37-1Relevant articles and documents
Synthesis and studies on the anticonvulsant activity of 5-alkoxy-[1,2,4]triazolo[4,3-a]pyridine derivatives
Guan,Zhang,Sun,Chang,Sui
, p. 372 - 377 (2012/10/29)
In this study, a series of new 5-alkoxy-[1,2,4]triazolo[4,3-a]pyridine derivatives was synthesized and their anticonvulsant activity and neurotoxicity was evaluated with the maximal electroshock and rotarod tests, respectively. The most promising compounds, 3p (5-(4-chlorophenoxy)-[1,2,4]triazolo[4,3-a] pyridine) and 3r (5-(4-bromophenoxy)-[1,2,4]triazolo[4,3-a]pyridine), showed a median effective dose of 13.2 and 15.8 mg/kg and had a protective index value of 4.8 and 6.9, respectively. For exploring the putative mechanism of action, compounds 3n, 3p and 3r were tested in chemically induced models. Georg Thieme Verlag KG Stuttgart.New York.
