501378-52-5

Basic information

• Product Name: 2-(benzyloxy)isonicotinonitrile
• Synonyms: 2-(benzyloxy)isonicotinonitrile;4-Pyridinecarbonitrile, 2-(phenylmethoxy)-;2-(benzyloxy)pyridine-4-carbonitrile
• CAS NO: 501378-52-5
• Molecular Formula: C13H10N2O
• Molecular Weight: 210.2313
• Mol File: 501378-52-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 339.7±32.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• PKA: 0.57±0.20(Predicted)
• CAS DataBase Reference: 2-(benzyloxy)isonicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzyloxy)isonicotinonitrile(501378-52-5)
• EPA Substance Registry System: 2-(benzyloxy)isonicotinonitrile(501378-52-5)

Safety Data

• Hazardous Substances Data: 501378-52-5(Hazardous Substances Data)

Usage

General Description

2-(benzyloxy)isonicotinonitrile, also known as BICN, is a chemical compound with the molecular formula C19H14N2O. It is a white to off-white solid with a faint odor. BICN is used in organic synthesis as a building block for the preparation of various pharmacologically active molecules. It is also used in the development and discovery of new drugs for the treatment of various diseases and conditions. BICN has also been studied for its potential antimicrobial, antifungal, and anticancer properties. 2-(benzyloxy)isonicotinonitrile has shown promise as a versatile and valuable tool in medicinal chemistry and drug development.

Relevant articles and documents

SUBSTITUTED 2- AMIDOQUINAZOL-4-ONES AS MATRIX METALLOPROTEINASE-13 INHIBITORS

The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]2 hydroxypropyl}5,6 dimethyl 4 oxo 1,4 dihydrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.