5014-48-2Relevant academic research and scientific papers
Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives
Pompeo, Matthew M.,Cheah, Jaime H.,Movassaghi, Mohammad
, p. 14411 - 14420 (2019)
A unified enantioselective total synthesis and anticancer evaluation of all known epoxide-containing communesin alkaloids and related derivatives is described. Our synthesis is predicated on the convergent and modular diazene-directed assembly of two comp
t-butyl hypochlorite: A powerful electrophilic aromatic ring chlorinating agent
Lengyel, Istvan,Cesare, Victor,Stephani, Ralph
, p. 1891 - 1896 (1998)
t-Butyl hypochlorite is an excellent aromatic ring chlorinating agent, under mild conditions, without any catalyst, of acetanilide. High regioselectivity is observed, the product being, nearly exclusively, para- chloroacetanilide.
Convergent and Biomimetic Enantioselective Total Synthesis of (-)-Communesin F
Lathrop, Stephen P.,Pompeo, Matthew,Chang, Wen-Tau T.,Movassaghi, Mohammad
supporting information, p. 7763 - 7769 (2016/07/06)
The first biomimetic enantioselective total synthesis of (-)-communesin F based on a late-stage heterodimerization and aminal exchange is described. Our synthesis features the expedient diazene-directed assembly of two advanced fragments to secure the con
