5016-85-3

Usage

Uses

Used in Fragrance Industry:
Phytyl acetate is used as a scent and flavoring agent for its distinctive floral, fruity, and green odor, adding a fresh and sweet fragrance to various products.
Used in Cosmetic Industry:
Phytyl acetate is utilized as an ingredient in skincare products due to its potential antioxidant and anti-inflammatory properties, promoting skin health and wellness.
Used in Consumer Product Formulation:
The natural origins and appealing aroma of phytyl acetate make it a popular choice for the formulation of a wide range of consumer products, enhancing their sensory appeal and marketability.

Upstream product

• 110109-83-6 7,11,15-trichloro-3,7,11,15-tetramethyl-2E-hexadecen-1-yl acetate 
• 253686-88-3 (E)-3,7,11,15-tetramethylhexadec-2-en-1-ol 
• 854039-21-7 cis-phytol 
• 108-24-7 acetic anhydride 
• 61691-98-3 geranylgeranyl acetate 
• 7541-49-3 3,7,11,15-tetramethyl-2-hexadecen-1-ol 

Relevant academic research and scientific papers

A new route to vitamin E Key-intermediates by olefin cross-metathesis

Ru-Catalyzed olefin cross-metathesis (CM) has been successfully applied to the synthesis of several phytyl derivatives (2b, 2d-f, 3b) with a trisubstituted C=C bond, as useful intermediates for an alternative route to α-tocopheryl acetate (vitamin E acetate; 1b) (Scheme 1). Using the second-generation Grubbs catalyst RuCl2(C21H 26N2)(CHPh)PCy3, (Cy = cyclohexyl; 4a) and Hoveyda-Grubbs catalyst RuCl2(C21H26N 2){CH-C6H4(O-iPr)-2} (4b), the reactions were performed with various C-allyl (5a-f, 7a,b) and O-allyl (8a-d) derivatives of trimethylhydroquinone-1-acetate as substrates. 2,6,10,14-Tetramethylpentadec-1-ene (6a) and derivatives 6c-e of phytol (6b) as well as phytal (6f) were employed as olefin partners for the CM reactions (Schemes 2 and 5). The vitamin E precursors could be prepared in up to 83% isolated yield as (E/Z)-mixtures.

A NEW ROUTE TO α-TOCOPHEROL, α-TOCOPHERYL ALKANOATES AND PRECURSORS THEREOF

The present invention is concerned with a novel process for the manufacture of (E/Z)-4-alkanoyloxy-3,5,6-trimethyl-2-phytylphenyI esters and silyl ethers, precursors of α- tocopherol and α-tocopheryl alkanoates, by cross-metathesis reaction of 2-alkenyl-3,5,6-trimethylhydroquinone dialkanoates or 4-alkanoyloxy-2-alkenyl-3,5,6-trimethylphenyI silylethers with 2,6,10,14-tetramethylpentadecene or a phytol derivative, e.g. phytyl acetate, in the presence of a cross-metathesis catalyst. As the cross-metathesis catalyst especially ruthenium metal carbene complexes are suitable which possess (a) ruthenium metal center(s), have an electron count of 16 or 18 and are penta- or hexa- coordinated. A further object of the invention is a process for the manufacture of α-tocopherol and α-tocopheryl alkanoates comprising this reaction.

SELECTIVE REDUCTION OF THE DISTANT DOUBLE BOND(S) IN GERANYL, FARNESYL AND GERANYL GERANYL DERIVATIVES.

Selective addition of hydrogen chloride on the non-proximal double bond(s) of the title compounds followed by hydrogenolysis led to selective hydrogenation of these double bond(s).