501644-56-0

Upstream product

• 30379-55-6 benzyloxyacetic acid 
• 19810-31-2 Benzyloxyacetyl chloride 
• 131744-19-9 (4S)-4-benzyl-1,3-oxazolidine-2-thione 

Downstream Products

• 1246212-47-4 (2R,3R)-2-(benzyloxy)-1-[(S)-4-benzyl-2-thioxooxazolidin-3-yl]-3-hydroxyhexan-1-one 
• 501644-66-2 (2R,3R)-2-Benzyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-pent-4-en-1-one 
• 501644-65-1 (2R,3R)-2-Benzyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-octan-1-one 
• 121701-09-5 (2S,3R)-2-benzyloxy-pent-4-ene-1,3-diol 
• 681830-22-8 WY₁₁₁₄₀₃ 
• 681830-23-9 (2S,3S,4R,6R)-2-Benzyloxy-1-((S)-4-benzyl-2-thioxo-oxazolidin-3-yl)-3-hydroxy-4-methyl-6-triethylsilanyloxy-heptan-1-one 

Relevant academic research and scientific papers

A stereoselective aldol approach for the total synthesis of herbarumin I and stagonolide A

A stereoselective total synthesis of phytotoxic compounds herbarumin I and stagonolide A has been achieved utilizing Crimmins protocol for non-Evans anti-aldol approach and a ring-closing olefin metathesis reaction as the key steps. Georg Thieme Verlag St

Anti-selective aldol reactions with titanium enolates of N-glycolyloxazolidinethiones

(Matrix presented). A highly diastereoselective anti aldol addition utilizing a variety of N-glycolyloxazolidinethiones has been developed. Enolization of an N-glycolyloxazolidinethione with titanium (IV) chloride and (-)-sparteine followed by addition of an aldehyde activated with additional TiCl4 resulted in highly anti-selective aldol additions, typically with no observable syn isomers. Allyl-protected glycolates demonstrated the highest levels of selection and yields, although O-benzyl and O-methyl glycolyloxazolidinethiones also performed well.