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501684-26-0

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501684-26-0 Usage

Chemical compound

2-Propenoic acid, 2-cyano-3-[(3-Methoxy-4-nitrophenyl)aMino]-, ethyl ester

Class

Ethyl esters

Functional groups

Cyano and amino

Physical state

Yellow solid

Uses

Raw material for pharmaceuticals and organic compounds

Derivative of

Acrylic acid

Commonly used in

Synthesis of various organic compounds

Valuable building block for

Production of important chemicals in pharmaceutical and chemical industries

Check Digit Verification of cas no

The CAS Registry Mumber 501684-26-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,1,6,8 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 501684-26:
(8*5)+(7*0)+(6*1)+(5*6)+(4*8)+(3*4)+(2*2)+(1*6)=130
130 % 10 = 0
So 501684-26-0 is a valid CAS Registry Number.

501684-26-0Relevant articles and documents

Syntheses and EGFR and HER-2 kinase inhibitory activities of 4-anilinoquinoline-3-carbonitriles: Analogues of three important 4-anilinoquinazolines currently undergoing clinical evaluation as therapeutic antitumor agents

Wissner, Allan,Brawner Floyd,Rabindran, Sridhar K.,Nilakantan, Ramaswamy,Greenberger, Lee M.,Shen, Ru,Wang, Yu-Fen,Tsou, Hwei-Ru

, p. 2893 - 2897 (2007/10/03)

The syntheses and biological evaluations of 4-anilinoquinoline-3-carbonitrile analogues of the three clinical lead 4-anilinoquinazolines Iressa, Tarceva, and CI-1033 are described. The EGFR and HER-2 kinase inhibitory activities and the cell growth inhibition of the two series are compared with each other and with the clinical lead EKB-569. Similar activities are observed between these two series.

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