501699-82-7Relevant academic research and scientific papers
Synthesis of novel (phenylalkyl)amines for the investigation of structure-activity relationships. Part 1. Mescalin derivatives
Trachsel, Daniel
, p. 3019 - 3026 (2007/10/03)
The synthesis and the spectroscopic data of 14 novel 4-substituted mescaline derivatives are reported. Starting from syringaldehyde (=4-hydroxy-3,5-dimethoxybenzaldehyde), several ethers were obtained from reaction with a series of corresponding saturated and unsaturated alkyl- and fluoroalkyl halides. Henry-reaction with MeNO2 or EtNO2 followed to afford the nitro-olefines, which were then reduced with AlH3 to the desired 2-phenytethyl- and 1-methyl-2-phenylethylamine derivatives.
